Figure 7.
Effect of SP on activation of HIV LTR-driven CAT activity in U38 cells. U38 cells were incubated with SP at different concentrations (10−10 to 10−6 M) or with CP-96,345 (10−6 M) and SP (10−8 M) (SP + CP) or with CP-96,345 (10−6 M) alone (CP only) or untreated (U38 only) for 48 h. The untreated U38 cells were used as baseline control. The CAT activity (cpm) of the treated U38 cells was expressed as percentage of that of untreated baseline control cells. The data shown are presented as the mean ± SD of triplicate cultures and are representative of three experiments (*, P < 0.05; SP-treated U38 vs. U38 only).