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. 2011;122:138–149.

TABLE 2.

In Vitro Leukocyte Abnormalities Associated with LAD-I

  • Neutrophil and monocyte adherence and spreading

  • Neutrophil aggregation

  • Neutrophil and monocyte chemotaxis

  • Neutrophil and monocyte phagocytosis

  • Neutrophil and monocyte complement receptor (CR3) activity

  • Neutrophil and monocyte C3-induced degranulation and respiratory burst (PMA-induced degranulation and burst normal)

  • Lymphocyte blastogenesis

  • Cytotoxic T-lymphocyte and NK-cell cytotoxicity