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. 2011;122:48–58.

TABLE 3.

Proposed Model For Curricular Organization by Mechanisms of Disease

Homeostatic Unit Primary elements
Ischemia Lung, cardiovascular system, erythrocytes, electron transfer, and ATP generation
Metabolism Gastrointestinal tract, liver, kidney, endocrine organs, energy storage
Neoplasia Genome and its variants, cell cycle
Inflammation Immune system, infectious diseases, microbiology
Neuropsychiatric Central and peripheral nervous system and special senses
Genetic Genome, cell cycle, conception, gender differences. The “4Ps”: personalized, predictive, preventive, participatory
Trauma Musculoskeletal system, skin
Socio-behavioral Health-care disparities, socio-economic effects, health care systems, environment, behavior