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. 2011;122:256–289.

TABLE 5.

Effects of Drug Classes on Serum Lipids (7)

Drug Class Total Cholesterol LDL-C HDL-C Triglycerides
Statins ↓ 15%–60% ↓ 15%–60% ↑ 5%–15% ↓ 15%–25%
Bile acid resins ↓ 20% ↓ 15%–25% ↑ 3%–5% Variable
Cholesterol absorption inhibitors ↓ 13% ↓ 17–20% ↑ 3% ↓ 8%
Nicotinic acid ↓ 25% ↓ 5%–25% ↑ 15%–35% ↓ 20%–50%
Fibric acid derivatives ↓ 15% Variable ↑ 10%–20% ↓ 20%–50%
Omega-3 fatty acids N/A N/A N/A ↓ 35%–50%