Terrestrial ecosystem emissions of reactive trace gases in the Eocene and Cretaceous. Simulated equilibrium global-scale (A) reactive biogenic trace gas emissions to the atmosphere for the 2 × CO2 (560 ppm) and 4 × CO2 (1,120 ppm) Eocene, and 4 × CO2 Cretaceous climates, relative to the preindustrial (PI) era. Panels B, C, and D, respectively, show zonal total fluxes for methane (CH4) from all biogenic sources (wetlands, biomass burning, oceans, and termites), isoprene released from forested regions, and oxides of nitrogen (NOx = NO + NO2) released from soils, and generated by biomass burning and lightning (see SI Text, SI Methods).