Table 7.
Model | BB | Bb | bb | Model | BB | Bb | bb |
AA | α | αθ21 | αθ21θ22 | AA | α | αθb | |
Aa | αθ11 | αθ11θ21 | αθ11θ21θ22 | Aa | αθa | αθa θb | |
aa | αθ11θ12 | αθ11θ12θ21 | αθ11θ12θ21θ22 | aa |
The parameters α, θ11, θ12, θ21, and θ22 control the prevalence p(D) (Equation(18)) and the heritability h2 (Equation(19)). For simplicity, let θ11 = θ12 = θa, θ21 = θ22 = θb