Skip to main content
. Author manuscript; available in PMC: 2012 Jan 1.
Published in final edited form as: Expert Rev Mol Diagn. 2011 Mar;11(2):183–196. doi: 10.1586/erm.10.119

Figure 1. Possible pathways for biomarker discovery in kidney transplantation.

Figure 1

Both a multidisciplinary team and multiple steps are needed to achieve the goal of moving biomarkers ‘from the bench to the bedside’. The process of discovery and validation of biomarkers that can be used for the routine evaluation of graft function requires a multidisciplinary team able to evaluate the clinical problem, understand the biology behind the clinical condition, and perform data analysis and integration. Moreover, external validation is required in prospective powered studies.

CNI: Calcineurin inhibitor.