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. Author manuscript; available in PMC: 2011 Sep 9.
Published in final edited form as: Chem Rev. 2011 Jan 14;111(3):1846–1913. doi: 10.1021/cr1002744

Table 15.

Ir-Catalyzed Enantioselective DcA of β-Ketoesters

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entry R1 R2 ee (%) time (h) yield (%) b:l
1 4-MeOC6H4 Ph 95 12 h 70 >99:1
2 Ph Ph 95 16 h 83 99:1
3 4-CF3C6H4 Ph 91 17 h 71 >99:1
4 2-Furyl Ph 94 3 h 73 98:2
5 Ph 2-napthyl 93 16 h 71 98:2
6 Ph 4-MeOC6H4 95 4 h 67 99:1
7 Me Ph 90 21 h 61 94:6
8 n-C5H11 Ph 89 22 h 52 80:20
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