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. Author manuscript; available in PMC: 2011 Sep 9.
Published in final edited form as: Chem Rev. 2011 Jan 14;111(3):1846–1913. doi: 10.1021/cr1002744

Table 7.

Asymmetric DcA of Vinylogous Ester Derivatives with PHOX-Ligand

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entry substrate solvent T (°C) product yield (%) ee (%)
1 24 tol 25 27 22–61 84–88
2 25 tol 50 27 19 79
3 25 tol 80 27 86 75
4 26 tol 50 28 86 92
5 26 PhH 50 28 61 92
6 26 THF 50 28 88 92
7 26 dioxane 50 28 90 91