Table 2.
Main plasma chemistry parameters analyzed
| Patient | GH peak |
TC |
TG |
G |
IGF-1 |
IGFBP3 |
|||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Pre | Post | Pre | Post | Pre | Post | Pre | Post | Pre | Post | ||
| 1 | 4.5 | 205 | 182 | 75 | 74 | 82 | 75 | 34.2 | 89 | 2.33 | 3.1 |
| 2 | 6.3 | 181 | 169 | 102 | 65 | 89 | 73 | 28.1 | 256 | 1.7 | 2.9 |
| 3 | 2.8 | 194 | 171 | 41 | 37 | 70 | 77 | 53 | 200 | 3.61 | 4.3 |
| 4 | 5.3 | 175 | 168 | 125 | 104 | 76 | 85 | 67.2 | 103.3 | 2.5 | 3.8 |
| 5 | 1.5 | 225 | 165 | 186 | 85 | 72 | 77 | 25 | 69.5 | 2.2 | 3.6 |
| 6 | 6.9 | 193 | 166 | 125 | 97 | 75 | 83 | 31 | 75 | 1.8 | 3.03 |
| 7 | 3.4 | 215 | 171 | 157 | 110 | 81 | 79 | 35 | 125 | 2.1 | 3.1 |
| 8 | 4.7 | 186 | 155 | 114 | 65 | 92 | 84 | 69.5 | 89.5 | 3 | 4.2 |
| 9 | 7.1 | 177 | 165 | 145 | 75 | 74 | 72 | 25 | 78 | 1.4 | 1.76 |
| 10 | 5.2 | 191 | 164 | 165 | 108 | 84 | 96 | 78 | 162 | 2.9 | 4.06 |
| 11 | 4.8 | 187 | 155 | 128 | 90 | 74 | 101 | 67 | 225 | 1.96 | 3.03 |
| Mean (SD) | 4.77 (1.71) | 193.54 (15.69) | 166.45 (7.51) | 123.90 (41.16) | 82.72 (22.25) | 79 (7.15) | 82 (9.27) | 46.63 (20.49) | 133.84 (66.41) | 2.31 (0.64) | 3.35 (0.73) |
| SS | 0.003*** | 0.003*** | ns | 0.003*** | 0.003*** | ||||||
Note:
***
P < 0.01 (Wilcoxon signed-rank test).
Abbreviations: GH peak, peak growth hormone (ng/mL) after insulin-induced hypoglycemia; TC, plasma total cholesterol (mg/dL); TG, plasma triglycerides (mg/dL); G, plasma glucose (mg/dL); IGF-1, plasma insulin-like growth factor (ng/mL); IGFBP3, plasma insulin-like growth factor binding protein 3 (μg/mL); SD, standard deviation of the mean; SS, statistical significance; ns, not significant; pre, pretreatment; post, post-treatment.