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. 2011 Jun 16;6(6):e19881. doi: 10.1371/journal.pone.0019881

Table 7. Recommendations for research on resveratrol for the coming years.

1 Clinical studies should be initiated, especially with focus on the effect of resveratrol on the development of cancers in colon and skin
2 Clinical studies should be initiated to test the potential cardio-vascular benefit of resveratrol
3 Elucidating the biological effects of resveratrol metabolites
4 Biodistribution and degradation of resveratrol in vivo, including the role of bacterial enzymes
5 Preparation of a resveratrol reference (international standard) product for analytical purposes
6 Standardized formulations for clinical studies
7 Combinatory effects of resveratrol with other compounds. This include development of relevant models
8 Interaction of resveratrol with drug metabolism (especially cytochrome P450 metabolism)
9 Identification/development of relevant biomarkers, relevant for the disease-prevention rather than disease treatment, depending on the relevant disease
10 Effect of resveratrol on inflammation as general condition relevant for several lifestyle diseases
11 Long term preclinical studies in nonhuman primates may be appropriate to determine the effect of resveratrol on diet-induced metabolic disorders, such as development of insulin resistance