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. 2011 Jun 16;6(6):e20609. doi: 10.1371/journal.pone.0020609

Figure 4. MyD88 is involved in rapid inflammasome activation in response to F. novicida infection.

Figure 4

BMDM from wild-type and MyD88−/− C57BL/6 mice were infected with wild-type (WT) and mglA mutant strains of F. novicida (MglA) at the indicated MOIs. At 6.5 h post-infection, (A) death of the infected macrophages was measured by LDH release and (B) the concentration of IL-18 in the supernatants was quantified by ELISA. Data are representative of four independent experiments. Error bars represent the standard deviation of triplicate samples. ** p<0.0090.