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. 2011 Jun 16;6(6):e21188. doi: 10.1371/journal.pone.0021188

Figure 1. Genome-wide linkage scan to detect susceptibility loci for five blood lipid phenotypes using QTL-ALL analysis using 316 pedigrees.

Figure 1

Linkage plots show significant signals at four chromosomal regions with allele sharing LOD (−log10 p value) on Y axis and chromosome distance (cM) on X axis. Significant linkage includes chromosome 5 near marker D5S2488 (p = 0.0031) for total cholesterol; chromosome 9 near marker D9S1122 (p = 0.0039) for LDL cholesterol; chromosome 10q21.2 near D10S1225 (p = 0.0011) for HDL cholesterol; and chromosome 22 near marker TCTA015M (p = 0.0016) for total cholesterol.