Table 1. Characteristics of Study Population Stratified by Gender and Disease (Mean ± SD).
T2D cases | Unaffected Relatives | p value** | ||
685 (412M/273F) | 185 (116M/69F) | |||
Age at recruitment (year) | M* | 52.42±11.36 | 44.71±15.20 | <0.0001 |
F | 55.93±10.88 | 48.60±13.60 | <0.0001 | |
Age at onset (years) | M | 45.80±10.65 | – | – |
F | 48.62±10.40 | – | – | |
Duration of T2D (years) | M | 7.82±7.42 | – | – |
F | 7.33±6.65 | – | – | |
BMI (kg/m2) | M | 26.90±4.23 | 26.89±4.53 | 0.876 |
F | 28.50±5.20 | 27.58±4.79 | 0.140 | |
WAIST (cm) | M | 95.50±10.40 | 93.2±11.55 | 0.040 |
F | 92.70±11.00 | 88.1±10.60 | <0.0001 | |
HIP (cm) | M | 95.8±8.20 | 96.0±8.50 | 0.875 |
F | 99.3±11.00 | 97.6±9.70 | 0.135 | |
WHR† | M | 0.99±0.07 | 0.97±0.07 | <0.0001 |
F | 0.94±0.07 | 0.90±0.07 | <0.0001 | |
Fasting Glucose (mg/dl) | M | 185.81±70.66 | 95.30±11.38 | <0.0001 |
F | 193.23±74.58 | 97.77±9.31 | <0.0001 | |
Total Cholesterol (mg/dl) | M | 177.18±44.34 | 174.54±45.86 | 0.525 |
F | 187.24±47.42 | 177.58±38.94 | 0.049 | |
Triglycerides (mg/dl) | M | 197.63±113.50 | 160.71±85.49 | <0.0001 |
F | 172.66±95.34 | 155.74±69.72 | 0.078 | |
HDL-cholesterol (mg/dl) | M | 38.11±12.44 | 39.21±10.01 | 0.321 |
F | 41.76±12.59 | 43.70±11.37 | 0.187 | |
LDL-cholesterol (mg/dl) | M | 99.98±35.68 | 98.36±32.96 | 0.619 |
F | 110.17±39.81 | 102.89±35.56 | 0.098 | |
VLDL-cholesterol (mg/dl) | M | 39.75±24.05 | 32.45±18.43 | 0.001 |
F | 34.77±19.18 | 31.13±13.84 | 0.056 |
*M - male, F- female; †Waist to hip ratio; **Difference between T2D cases and unaffected relatives.