Table 1. Basic characteristics of the study populations: Discovery and extension sets of community controls and gastric cancer cases from the KMCC, Chungnam University Hospital and Hanyang University GURI Hospital.
| Discovery phasea | Extension phaseb | Total gastric cancer cases vs. controls | ||||||||
| Case(N = 81) | Control(N = 85) | p-value | Case(N = 398) | Control(N = 360) | p-value | Case(N = 479) | Control(N = 445) | p-value | ||
| Age | Mean (SD) | 64.2 (±7.9) | 63.3 (±8.0) | 0.44 | 61.6 (±10.4) | 63.2 (±8.3) | 0.02 | 62.0 (±10.1) | 63.2 (±8.2) | 0.06 |
| Sex | Female | 26 (32.1) | 26 (30.6) | 0.83 | 131 (32.9) | 115 (31.9) | 0.78 | 157 (32.8) | 141 (31.7) | 0.72 |
| H.pylori infection | Positive (+) | 72 (88.9) | 68 (80.0) | 0.11 | 353 (88.7) | 309 (85.8) | 0.24 | 425 (88.7) | 377 (84.7) | 0.07 |
| CagA | Positive (+) | 78 (96.3) | 74 (87.1) | 0.03 | 366 (91.9) | 318 (88.3) | 0.09 | 444 (92.7) | 392 (88.1) | 0.02 |
| VacA | Positive (+) | 50 (61.7) | 46 (54.1) | 0.32 | 279 (70.1) | 240 (66.7) | 0.31 | 329 (68.7) | 286 (64.3) | 0.16 |
| Smoking status c | Ever smokers | 52 (64.2) | 47 (55.3) | 0.24 | 247 (62.1) | 196 (54.4) | 0.10 | 300 (62.6) | 243 (54.6) | 0.01 |
| Drink status d | Ever drinkers | 46 (56.8) | 50 (58.8) | 0.79 | 250 (62.8) | 213 (59.2) | 0.28 | 296 (61.9) | 263 (59.1) | 0.38 |
| Gastric ulcer history | Positive (+) | 14 (21.9) | 9 (14.1) | 0.25 | 62 (17.8) | 53 (19.1) | 0.69 | 76 (18.5) | 62 (18.1) | 0.91 |
a
Incidence gastric cancer cases identified in December 2005 and their age-sex matched controls from the KMCC.
b
Newly identified and prevalent gastric cancer cases from the KMCC and newly enrolled gastric cancer cases from Chungnam University Hospital and Hanyang University GURI Hospital and their age-sex matched controls from the KMCC.
c
Ever smokers were defined as former and current smokers.
d
Ever drinkers were defined as former and current drinkers.