Table 1. Basic characteristics of the study populations: Discovery and extension sets of community controls and gastric cancer cases from the KMCC, Chungnam University Hospital and Hanyang University GURI Hospital.
Discovery phasea | Extension phaseb | Total gastric cancer cases vs. controls | ||||||||
Case(N = 81) | Control(N = 85) | p-value | Case(N = 398) | Control(N = 360) | p-value | Case(N = 479) | Control(N = 445) | p-value | ||
Age | Mean (SD) | 64.2 (±7.9) | 63.3 (±8.0) | 0.44 | 61.6 (±10.4) | 63.2 (±8.3) | 0.02 | 62.0 (±10.1) | 63.2 (±8.2) | 0.06 |
Sex | Female | 26 (32.1) | 26 (30.6) | 0.83 | 131 (32.9) | 115 (31.9) | 0.78 | 157 (32.8) | 141 (31.7) | 0.72 |
H.pylori infection | Positive (+) | 72 (88.9) | 68 (80.0) | 0.11 | 353 (88.7) | 309 (85.8) | 0.24 | 425 (88.7) | 377 (84.7) | 0.07 |
CagA | Positive (+) | 78 (96.3) | 74 (87.1) | 0.03 | 366 (91.9) | 318 (88.3) | 0.09 | 444 (92.7) | 392 (88.1) | 0.02 |
VacA | Positive (+) | 50 (61.7) | 46 (54.1) | 0.32 | 279 (70.1) | 240 (66.7) | 0.31 | 329 (68.7) | 286 (64.3) | 0.16 |
Smoking status c | Ever smokers | 52 (64.2) | 47 (55.3) | 0.24 | 247 (62.1) | 196 (54.4) | 0.10 | 300 (62.6) | 243 (54.6) | 0.01 |
Drink status d | Ever drinkers | 46 (56.8) | 50 (58.8) | 0.79 | 250 (62.8) | 213 (59.2) | 0.28 | 296 (61.9) | 263 (59.1) | 0.38 |
Gastric ulcer history | Positive (+) | 14 (21.9) | 9 (14.1) | 0.25 | 62 (17.8) | 53 (19.1) | 0.69 | 76 (18.5) | 62 (18.1) | 0.91 |
Incidence gastric cancer cases identified in December 2005 and their age-sex matched controls from the KMCC.
Newly identified and prevalent gastric cancer cases from the KMCC and newly enrolled gastric cancer cases from Chungnam University Hospital and Hanyang University GURI Hospital and their age-sex matched controls from the KMCC.
Ever smokers were defined as former and current smokers.
Ever drinkers were defined as former and current drinkers.