Skip to main content
. 2011 Jun 16;6(6):e21228. doi: 10.1371/journal.pone.0021228

Table 1. Histology Scoring.

Host Response Score
Inflammation 0–4 PMNs/HPF 1
5–20 PMNs/HPF 2
>20 PMNs/HPF 3
Diffuse band-like infiltrate (diffuse to numerous to count) 4
Depth of Inflammation Inflammatory cells not present 1
Inflammatory cells present within one-third of tissue matrix 2
Inflammatory cells present within two-third of tissue matrix 3
Inflammatory cells present within entire tissue matrix (full-thickness) 4
Neo-Vascularization No or rare capillaries 1
Few capillaries (<5 capillaries/HPF) 2
Many capillaries (5–10 capillaries/HPF) 3
Abundant capillaries present (granulation tissue) 4
Cellular re-population Tissue matrix containing no nuclei of fibroblasts 1
Tissue matrix containing nuclei of fibroblasts within one-third of matrix 2
Tissue matrix containing nuclei of fibroblasts within two-third of matrix 3
Tissue matrix containing nuclei of fibroblasts within full thickness of matrix 4

PMNs, polymorphonuclear cells; HPF, high power field;

*Cellular re-population of the acellular collagenous matrix by cellular collagen containing nuclei of fibroblast.

Note. 40 x magnifications.