Table 1. Histology Scoring.
Host Response | Score | |
Inflammation | 0–4 PMNs/HPF | 1 |
5–20 PMNs/HPF | 2 | |
>20 PMNs/HPF | 3 | |
Diffuse band-like infiltrate (diffuse to numerous to count) | 4 | |
Depth of Inflammation | Inflammatory cells not present | 1 |
Inflammatory cells present within one-third of tissue matrix | 2 | |
Inflammatory cells present within two-third of tissue matrix | 3 | |
Inflammatory cells present within entire tissue matrix (full-thickness) | 4 | |
Neo-Vascularization | No or rare capillaries | 1 |
Few capillaries (<5 capillaries/HPF) | 2 | |
Many capillaries (5–10 capillaries/HPF) | 3 | |
Abundant capillaries present (granulation tissue) | 4 | |
Cellular re-population | Tissue matrix containing no nuclei of fibroblasts | 1 |
Tissue matrix containing nuclei of fibroblasts within one-third of matrix | 2 | |
Tissue matrix containing nuclei of fibroblasts within two-third of matrix | 3 | |
Tissue matrix containing nuclei of fibroblasts within full thickness of matrix | 4 |
PMNs, polymorphonuclear cells; HPF, high power field;
*Cellular re-population of the acellular collagenous matrix by cellular collagen containing nuclei of fibroblast.
Note. 40 x magnifications.