Figure 5. NM and SG morphotypes are selected in continuous cultures supplemented with bile salts.

(A) Evolution over time (in days) of the CFU of motility morphotypes following inoculation of chemostats with the WT MG1655 strain. Non-motile (NM) variants are rapidly selected. (B) The same evolution is observed when bile salts are added to the chemostat culture medium at 0.8% w/v. In addition to the non-motile variants, small granulous colonies (SG) are selected.