Table 3.
No. of tumors | Average percent (% ×100) | Range of percent (% ×100) | |
Gene name | Methylated* | Tumor Methylation | Tumor Methylation |
ERα | 26 | 32 | 6–84 |
TWIST | 37 | 38 | 6–93 |
Cyclin D2 | 24 | 44 | 7–93 |
CDH1 | 2 | 19 | 17–21 |
APC | 44 | 41 | 8–91 |
RASSF1A | 62 | 38 | 6–96 |
HIN1 | 28 | 62 | 5–95 |
RARb | 40 | 37 | 6–93 |
BRCA1 | 23 | 47 | 7–84 |
BRCA2 | 7 | 33 | 7–89 |
Numer of tumors methylated: Total number of tumors that exceeded a methylation threshold of 5.0 percent for each of ten genes. Range of percent tumor methylation and percent tumor methylation: Range of percent methylation and mean methylation values, respectively for those genes that exceeded a 5.0% methylation threshold.