Table 2.
In vitro study | Pre-ECP PBMC | Post-ECP PBMC | Pre-ECP BC | Post-ECP BC |
---|---|---|---|---|
Mixed leukocyte culture: | ||||
% Alloreactivity, median, (range) | 100% | 92.1(59.32–178.2) | 48.7(21.3–375) | 3.5(0.08–19.6) |
NK-cell function: | ||||
% specific lysis, median, (range) | 53.8 (14–57.3) | 32 (28–57) | 38.7 (16.2–50.4) | 16.6 (8.7–33.2) |
Apoptosis-early: | ||||
% Annexin-V FITC+/Pl− Mean, (standard deviation) | 14.4 (5.2–23.6) | 16.9 (5.3–29.1) | 25 (15.4–40) | 34.5 (10.6–5.3) |
Apoptosis-late: | ||||
% Annexin-V FITC+/Pl− Mean, (standard deviation) | 16.2 (6.5–27.7) | 19.1 (7.9–32.7) | 31.2 (15.4–40) | 65.2 (45.8–81.3) |