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. Author manuscript; available in PMC: 2013 Feb 1.
Published in final edited form as: Neurobiol Aging. 2010 Dec 8;33(2):427.e1–427.e14. doi: 10.1016/j.neurobiolaging.2010.10.013

Figure 2.

Figure 2

Spontaneous and nomifensine-induced locomotor activity in 12 month old Gdnf+/− and WT mice. (A) Saline-injected (indicated by arrow, 0.01ml/g body weight) Gdnf+/− mice showed significantly decreased total distance traveled as compared to saline-treated WT mice [P < 0.01]. (B) Gdnf+/− mice showed greater nomifensine-induced (indicated by arrow, 7.5mg/kg, i.p.) locomotor activity, compared to WT mice [F7,84 = 3.119, P < 0.01].