Table 1.
Age group differences in white matter integrity
| FA |
AD(× 10−3 mm2/sec) |
RD(× 10−4 mm2/sec) |
|||||||
|---|---|---|---|---|---|---|---|---|---|
| Tracts | Younger | Older | t | Younger | Older | t | Younger | Older | t |
| ILF Left | .59 ± .03 | .54 ± .04 | −4.5* | 1.34 ± 0.04 | 1.29 ± 0.06 | −2.9* | 4.78 ± 0.29 | 5.12 ± 0.37 | 2.9* |
| ILF Right | .57 ± .04 | .53 ± .03 | −3.0* | 1.30 ± 0.05 | 1.27 ± 0.06 | −1.4 | 4.82 ± 0.37 | 5.18 ± 0.34 | 2.9* |
| SLF Left | .49 ± .05 | .47 ± .03 | −1.8 | 1.08 ± 0.04 | 1.09 ± 0.05 | 0.2 | 4.94 ± 0.39 | 5.21 ± 0.29 | 2.3† |
| SLF Right | .47 ± .05 | .45 ± .03 | −1.2 | 1.07 ± 0.04 | 1.08 ± 0.05 | 0.7 | 5.13 ± 0.39 | 5.37 ± 0.28 | 2.1* |
| Genu | .53 ± .03 | .48 ± .03 | −4.2* | 1.30 ± 0.05 | 1.31 ± 0.06 | 0.1 | 5.11 ± 0.35 | 5.77 ± 0.55 | 3.8* |
| Splenium | .61 ± .03 | .60 ± .03 | −0.6 | 1.50 ± 0.09 | 1.47 ± 0.06 | −0.9 | 5.05 ± 0.52 | 5.03 ± 0.31 | −0.1 |
Notes. Fractional anisotropy (FA), axial diffusivity (AD), and radial diffusivity (RD) values are presented as mean ± standard deviation for each white matter tract separately for younger and older adults.
significant effects at p < .008 (Bonferroni-corrected for 6 comparisons per measure of white matter integrity).
significant effects at p < .05.
ILF = inferior longitudinal fasciculus. SLF = superior longitudinal fasciculus.