Skip to main content
. Author manuscript; available in PMC: 2012 Jul 15.
Published in final edited form as: Cancer. 2011 Feb 1;117(14):3156–3162. doi: 10.1002/cncr.25735

Table 3.

Differences, by UGT1A1*28 genotype, in time from diagnosis, metastatic disease and treatment

6/6 6/7 7/7 ALL (n=329)
n=137 n=153 n=39
Time (in weeks) from initial diagnosis and treatment start (p=0.014)&
Median 62 39 42 48
Inter-quartile Range 22–122 11–86 11–97 13–109
Time (in weeks) from 1st metastasis/recurrence to treatment start (p=0.13)&
Median 13 11 13 12
Inter-quartile Range 6–38 5–23 8–38 6–30
Treatment protocol^ (p=0.69)
FOLFIRI 42% 37% 28% 38%
IFL 37% 44% 44% 41%
Other irinotecan-based (TEGAFIRI, XELIRI) 21% 19% 28% 21%
*

chi-Square test

&

Kruskal-Wallis test

^

In patients with genotype and full oncological follow-up