Table 3.
0 g/kg | 2.5 g/kg | 3.0 g/kg | 3.5 g/kg | |||
---|---|---|---|---|---|---|
ADULT | D2 | BEC (mg/dL) | 222.5 ± 15.3 | 186.6 ± 14.3 | 185.4 ± 3.9 | 172.4 ± 14.8 |
n | 21 | 14 | 12 | 12 | ||
B6 | BEC | 186.9 ± 15.9 | 186.3 ± 29.3 | 159.4 ± 28.5 | 174.6 ± 14.8 | |
n | 19 | 15 | 9 | 9 | ||
ADOLESCENT | D2 | BEC | 235.9 ± 11.6 | 228.7 ± 14.1 | 166.0 ± 17.6 | 173.7 ± 11.9 |
n | 13 | 15 | 10 | 10 | ||
B6 | BEC | 189.2 ± 13.8 | 208.3 ± 9.2 | 171.9 ± 11.9 | 169.2 ± 14.5 | |
n | 18 | 12 | 15 | 12 |
Although analysis of the blood ethanol concentration following the challenge dose of 2.0g/kg revealed no interaction of age, genotype and dose, there was a main effect of genotype and dose (p’s <0.05). Specifically, the repeated-saline group demonstrated a greater BEC than the 3.0g/kg and 3.5g/kg groups, and D2 mice exhibited greater BEC’s than B6 mice.