Table 5.
Analysis of Statin and NSAID or Aspirin use and Odds of Colorectal Cancer Stratified by IBD
| Variable | Case | Control | Unadjusted OR | Adjusted OR*# |
|---|---|---|---|---|
| No IBD | ||||
| Statin use: | 0.49 (0.39, 0.62) | 0.56 (0.44, 0.72) | ||
| Yes | 115 (6.1) | 224 (11.8) | P<0.001 | P<0.001 |
| No | 1767 (93.9) | 1676 (88.2) | ||
| NSAID/ASA use: | 0.60 (0.51, 0.71) | 0.62 (0.53, 0.73) | ||
| Yes | 310 (16.5) | 474 (24.9) | P<0.001 | P<0.001 |
| No | 1572(83.5) | 1426 (75.1) | ||
| IBD | ||||
| Statin use: | 0.07 (0.01, 0.78) | 0.10 (0.01, 1.31) | ||
| Yes | 1 (2.6) | 5 (23.8) | P=0.029 | P=0.080 |
| No | 38 (97.4) | 16 (76.2) | ||
| NSAID/ASA use: | 0.47 (0.12, 1.86) | 0.49 (0.07, 3.32) | ||
| Yes | 5 (12.8) | 5 (23.8) | P=0.283 | P=0.461 |
| No | 34 (87.2) | 16 (76.2) |
*
Unmatched analysis.
#
Analyses adjusted for age, sex, ethnic group, presence or absence of sports participation, level of vegetable consumption, smoking status and history of colorectal cancer in a first degree relative.