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. Author manuscript; available in PMC: 2012 Sep 1.
Published in final edited form as: J Nutr Biochem. 2010 Dec 15;22(9):812–819. doi: 10.1016/j.jnutbio.2010.06.011

Figure 2.

Figure 2

Effect of dietary abscisic acid (ABA) supplementation on colon histopathology in PPAR γ-expressing and T cell-specific PPAR γ null mice. PPAR γ flfl;CD4 Cre− (wt) and PPAR γ flfl; CD4 Cre+ (CD4cre) were fed ABA-supplemented (100 mg/kg) or control diets for 35 days and challenged with 2.5% dextran sodium sulfate (DSS) or water (no DSS) for 7 days. Representative photomicrographs from wt, control (A), wt, ABA (B), CD4cre, control (C), and CD4cre, ABA (D) groups are illustrated (Original magnification, 40×). All specimens underwent blinded histological examination and were scored (1-4) on epithelial erosion (E), mucosal wall thickening (F), and leukocyte infiltration (G). Data are represented as mean ± standard error. Statistically significant differences (P<0.05) between groups are indicated with different letter subscripts (n=8 mice/group) in three independent experiments.