Table 3.
ROC Curve Area Values for PI of Insonated Arteries in Subjects with AD and NDC
| Insonated Artery |
ROC Curve Area |
Standard Error |
P Value | Sample Size - AD |
Sample Size - NDC |
PI Cut off |
Sensitivity (%) |
Specificity (%) |
|---|---|---|---|---|---|---|---|---|
| Lsiph | 0.75 | 0.05 | < 0.001 | 40 | 50 | 1.25 | 72.0 | 67.5 |
| RdMCA | 0.72 | 0.06 | < 0.001 | 36 | 49 | 1.15 | 75.5 | 63.9 |
| RICA | 0.71 | 0.05 | < 0.001 | 41 | 50 | 1.25 | 62.0 | 75.6 |
| RpMCA | 0.70 | 0.06 | < 0.001 | 39 | 49 | 1.05 | 55.1 | 82.1 |
| LPCA | 0.70 | 0.06 | < 0.001 | 34 | 43 | 1.05 | 65.1 | 67.7 |
| dBA | 0.69 | 0.06 | < 0.001 | 36 | 50 | 1.05 | 60.0 | 72.2 |
| LACA | 0.68 | 0.06 | 0.01 | 35 | 45 | 1.05 | 62.2 | 62.9 |
| LpMCA | 0.68 | 0.06 | < 0.001 | 37 | 48 | 0.97 | 29.2 | 89.2 |
| pBA | 0.66 | 0.06 | 0.01 | 38 | 50 | 0.92 | 42.0 | 81.6 |
| LdMCA | 0.65 | 0.06 | 0.02 | 33 | 45 | 1.15 | 57.8 | 69.7 |
| RPCA | 0.65 | 0.06 | 0.02 | 34 | 46 | 0.89 | 32.6 | 91.2 |
| Rsiph | 0.65 | 0.06 | 0.02 | 40 | 49 | 1.05 | 34.7 | 85.0 |
| RVA | 0.63 | 0.06 | 0.03 | 37 | 49 | 0.95 | 26.5 | 89.2 |
| LICA | 0.61 | 0.06 | 0.08 | 41 | 49 | 1.25 | 61.2 | 53.7 |
| RACA | 0.58 | 0.06 | 0.21 | 38 | 49 | 0.95 | 26.5 | 86.8 |
| LVA | 0.50 | 0.06 | 1.00 | 38 | 49 | 0.94 | 18.4 | 89.5 |
Abbreviations: ROC, receiver-operator characteristic; AD, Alzheimer’s disease; NDC, non-demented control; PI, pulsatility index; Lsiph, left siphon; RdMCA, right distal middle cerebral artery; RICA, right internal carotid artery; RpMCA, right proximal middle cerebral artery; LPCA, left posterior cerebral artery; dBA, distal basilar artery; LACA, left anterior cerebral artery; LpMCA, left proximal middle cerebral artery; pBA, proximal basilar artery; LdMCA, left distal middle cerebral artery; RPCA, right posterior cerebral artery; Rsiph, right siphon; RVA, right vertebral artery; LICA, left internal carotid artery; RACA, right anterior cerebral artery; LVA, left vertebral artery.