Table 3.
Association of Occlusion with AD
Measure of Occlusion | n (NDC/AD) | Adjusted1 Odds Ratio | p |
---|---|---|---|
Mean index of occlusion | |||
ACA | 36/60 | 1.03 | .065 |
BA | 35/60 | 1.05 | .015 |
ICA | 36/60 | 1.05 | .014 |
MCA | 36/60 | 1.06 | .003 |
PCA | 35/60 | 1.04 | .0099 |
VA | 31/49 | 1.04 | .052 |
All arteries | 36/60 | 1.06 | .006 |
Percentage of sections ≥60% occluded | |||
ACA | 36/60 | 1.01 | .101 |
BA | 35/60 | 1.02 | .018 |
ICA | 36/60 | 1.01 | .084 |
MCA | 36/60 | 1.03 | .0003 |
PCA | 35/60 | 1.01 | .027 |
VA | 31/49 | 1.02 | .022 |
All arteries | 36/60 | 1.03 | .002 |
Models were adjusted for age at death, gender and presence of an apolipoprotein E *E4 allele. The maximum possible sample size in this multivariate analyses for the AD group is 60, due to the absence of apolipoprotein genotyping of one individual.
Abbreviations: NDC, non-demented control; AD, Alzheimer's disease; ACA, anterior cerebral arteries; BA, basilar artery; ICA, internal carotid arteries; MCA, middle cerebral arteries; PCA, posterior cerebral arteries; VA, vertebral arteries.