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. 2001 Mar 20;98(7):4016–4021. doi: 10.1073/pnas.071389098

Figure 2.

Figure 2

Dwarfism and mortality in Nppc−/− mice. (a) Survival curves of Nppc+/+ (○), Nppc+/− (□), and Nppc−/− (▵) mice. (b) Gross appearance of Nppc+/+ and Nppc−/−mice at 10 weeks of age. (c and d) Growth curves of Nppc+/+ (○), Nppc+/− (□), and Nppc−/− (▵) mice. (c) Males. (d) Females. (e) Soft x-ray analysis of Nppc+/+ and Nppc−/− mice at 10 weeks of age. Bone dimensions in e are of Nppc+/+ (open bars) and Nppc−/− (closed bars) mice (n = 4). TL, tibial length; FL, femoral length; VL, fifth lumbar vertebral length; CL, naso-occipital length of the calvarium; CW, maximal interparietal distance of the calvarium. *, P < 0.05 vs. Nppc+/+ mice.