Figure 8.

The ketone-induced gene signature predicts recurrence, metastasis and decreased overall survival in luminal A breast cancers. Survival curves within low and high ketone signature-expressing populations are shown within the luminal A subtype for (A) metastasis-free survival, (B) relapse-free survival and (C) overall survival. This signature contains ∼4,141 genes (See Sup. Table 2). In (C), it is important to note that overall survival data were available for a smaller number of luminal A breast cancer cases.