Fig. 1.

(A) Alignment of the RamR palindromic binding sequence at the pI and pII promoter in Salmonella, Klebsiella, Enterobacter and Citrobacter spp. (B) Regulatory elements within the romA–ramA locus. The inverted palindromic sequences are in bold and indicated by arrows. The two putative promoters are depicted as pI and pII. The transcription start of ramA as mapped by 5′ RACE (rapid amplification of cDNA ends) is indicated by +1. The translation start site of both romA and ramA is indicated in bold and superscript. All promoter changes are in grey, with those hypothesised to be associated with ramA overexpression in grey and with an asterisk. IR, intergenic region.