Table 1.
Sample characteristics
| Characteristics | All subjects (n = 21) | Healthy controls (n = 10) | BD-euthymic (n = 6) | BD-depressed (n = 5) |
|---|---|---|---|---|
| All subjects | ||||
| Age, mean (SD) | 32.0 (8.8) | 30.5 (9.9) | 32.0 (9.6) | 36.8 (4.1) |
| Age of menarche, mean (SD) | 11.7 (4.3) | 12.4 (2.0) | 12.8 (1.5) | 8.8 (8.2) |
| Length of cycles, days, mean (SD) | 29.0 (3.5) | 29.0 (2.6) | 30.0 (3.3) | 28.0 (5.5) |
| No. ovulatory cycles in the study | 3.0 | 2.4 | 2.3 | 3.2 |
| No. early follicular phases | 26 | 8 | 7 | 11 |
| No. late luteal phases | 29 | 15 | 5 | 9 |
| Patients with bipolar disorder | ||||
| Age of onset, mean (SD) | – | – | 16.8 (6.1) | 16.6 (6.2) |
| Years of illness, mean (SD) | – | – | 15.2 (9.1) | 20.2 (3.4) |
| ≥ 2 antimanic drugs, n (%) | 7 (33) | 0 | 5 (83) | 2 (40) |
| 1 antimanic drug, n (%) | 3 (14) | 0 | 1 (17) | 2 (40) |
| No antimanic drugs, n (%) | 1 (5) | – | 0 (0) | 1 (20) |
| Antidepressant therapy, n (%) | 8 (38) | 0 | 3 (50) | 5 (100) |
| Valproate therapy, n (%) | 4 (17) | 0 | 3 (50) | 1 (20) |
BD = bipolar disorder.