Table 3.

Blood tests for pulmonary arterial hypertension work-up.

• CBC, urinalysis, Chem-20 including liver function profile, BNP

• Coagulation studies

• Factor VIII

• Von Willebrand Ag

• Von Willebrand ristocetin cofactor

• Protein C

• Protein S

• Factor II, V, VII

• Factor V Leiden

• Serum viscosity

• Serum protein electrophoresis

• Hemoglobin electrophoresis

• Quantitative immunoglobulins

• Fractionated plasma catecholamines

• HIV test

• Thyroid function tests

• Connective Tissue disease work-up

• Lupus anticoagulant

• ESR

• ANA

• Anti-DNA

• Anticardiolipin antibodies

• CH50 complement and components

• Special ANAs

• Anticentromere

• Rheumatoid factor

• Consider genetic BMPR2 testing

Ag, antigen; ANA, antinuclear antibodies; CBC, complete blood counts; CH50, total serum hemolytic component; ESR, erythrocyte sedimentation rate; HIV, human immunodeficiency virus; HLA, human leukocyte antigen; BMPR2, bone-morphogenetic protein receptor 2.