Table 5.

Univariate analysis for grades 3-4 late subcutaneous toxicity in the whole series of patients (n = 26) and in patients who received higher doses of RT (n = 19)

	HR	(95% CI)	P
Whole series
Age	1.012	(0.975-1.012)	0.535
Received dose	1.079	(0.980-1.189)	0.123
Maximum dose	1.054	(0.991-1.121)	0.096
Bra size	1.056	(1.003-1.111)	0.037
Systemic treatment	1.084	(0.351-3.347)	0.888
Low DSB-High RIA 1Gy	0.564	(0.233-1.370)	0.206
Low DSB-High RIA 2Gy	0.510	(0.204-1.277)	0.150
Low DSB-High RIA 8Gy	0.642	(0.270-1.523)	0.314
Higher dose (≥81.6Gy)
Low DSB-High RIA 1Gy	0.252	(0.077-0.826)	0.023
Low DSB-High RIA 2Gy	0.197	(0.053-0.735)	0.016
Low DSB-High RIA 8Gy	0.240	(0.074-0.778)	0.017

Abbreviations: HR = hazard ratio; CI = confidence interval