Table 4.
Outputs of all three models using standardized set of input parameters for hypothetical countries in the subA-Saharan African (SSA) region, Southeast Asian (SEA) region and Latin America and the Caribbean (LAC) region
| Hypothetical country, SSA region | Hypothetical country, SEA region | Hypothetical country, LAC region | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Results | ADIP | Pan-American Health Organization (PAHO) TriVac | SUPR | ADIP | PAHO TriVac | SUPR | ADIP | PAHO TriVac | SUPR | ||||||
| D | S | D/S | D | S | D | S | D/S | D | S | D | S | D/S | D | S | |
| Outcomes: | |||||||||||||||
| Life years gained | 5,657 | 1,228 | 18,500a | 1,511 | 1,781 | 109,405 | 22,584 | 295,344a | 1,511 | 2,228 | 17,568 | 7,648 | 99,204a | 1,511 | 3,847 |
| Death averted | - | - | 567a | 18 | 30 | - | - | 8,786a | 18 | 32 | - | - | 2,924a | 18 | 53 |
| QALYs gained | - | - | 2,438 | 3,523 | - | - | - | 2,438 | 4,123 | - | - | - | 2,438 | 5,474 | |
| DALYs averted | 5,681 | 1,254 | 18,950a | - | - | 109,839 | 23,084 | 301,953a | - | - | 17,640 | 7,761 | 100,736a | - | - |
| Costs (US$): | |||||||||||||||
| Incremental cost per live birth population | -74,020 | 4,863,640 | 72,796,429 | 61,454,589 | -36,736,421 | 84,234,567 | 83,385,318 | 1,025,138,030 | 61,454,589 | 40,278,151 | -540,048 | 10,300,512 | 160,611,146 | 61,454,589 | -28,181,083 |
| Incremental cost per person | -1.23 | 80 | 60 | 84 | -607 | 90 | 89 | 55 | 84 | 43 | -3.85 | 73 | 57 | 84 | -201 |
| Incremental cost-effectiveness ratio (US$): | |||||||||||||||
| Incremental cost per DALYs averted | - | 3,878 | 3,842 | - | - | 767 | 3,612 | 3,395 | - | - | - | 1,327 | 1,594 | - | - |
| Incremental cost per life year gained | - | 3,961 | 3,935 | 40,683 | - | 770 | 3,692 | 3,471 | 40,683 | 18,081 | - | 1,347 | 1,619 | 40,683 | - |
| Incremental cost per death averted | - | 127,290 | - | - | - | 25,763 | 123,289 | - | - | - | - | 45,206 | - | - | - |
| Incremental cost per case averted | - | - | 1,348 | - | - | - | 1,311 | - | - | - | - | 1,324 | - | - | |
| Incremental cost per hospitalization averted | - | - | 9,278 | - | - | - | - | 10,706 | - | - | - | - | 9,047 | - | - |
| Incremental cost per death averted | - | - | 128,397 | 3,336,028 | - | - | - | 116,673 | 3,336,028 | 1,276,894 | - | - | 54,935 | 3,336,028 | - |
| Incremental cost per QALYs | - | - | - | 25,210 | - | - | - | - | 25,210 | 9,770 | - | - | - | 25,210 | - |
Default means the outputs using the predefined model inputs. Standardized means the outputs using the standardized model input.
aPer 20 cohorts.
ADIP = Pneumo ADIP; SUPR = Supremes; D = default; S = standardized