Table 1.
Results of supervised feature selection on the first 100 important protein attributes (with value equal to 1) contributing to halo-stability of studied proteins.
| No | Field | Value | Rank | No | Field | Value | Rank |
|---|---|---|---|---|---|---|---|
| 1 | Freq of Leu-Leu | 1.0 | Important | 51 | Freq of Tyr-Leu | 1.0 | Important |
| 2 | Freq of Phe-Pro | 1.0 | Important | 52 | Freq of Glu | 1.0 | Important |
| 3 | Freq of Leu-Ile | 1.0 | Important | 53 | Freq of Tyr-Ile | 1.0 | Important |
| 4 | Freq of Glu-Met | 1.0 | Important | 54 | Freq of carbon | 1.0 | Important |
| 5 | Freq of Trp-Lys | 1.0 | Important | 55 | Freq of Ile-Ile | 1.0 | Important |
| 6 | Freq of Leu | 1.0 | Important | 56 | Freq of Ile-Ala | 1.0 | Important |
| 7 | Freq of Val-Phe | 1.0 | Important | 57 | Freq of Met | 1.0 | Important |
| 8 | Freq of Trp-Pro | 1.0 | Important | 58 | Freq of Other | 1.0 | Important |
| 9 | Freq of Lys-Leu | 1.0 | Important | 59 | Freq of Val | 1.0 | Important |
| 10 | Freq of Leu-His | 1.0 | Important | 60 | Freq of Ala-Lys | 1.0 | Important |
| 11 | Freq of Leu-Arg | 1.0 | Important | 61 | Freq of Arg-Ile | 1.0 | Important |
| 12 | Freq of Ile | 1.0 | Important | 62 | Freq of Ile-Gly | 1.0 | Important |
| 13 | Freq of Val-Lys | 1.0 | Important | 63 | Freq of Lys-Thr | 1.0 | Important |
| 14 | Freq of Pro-Tyr | 1.0 | Important | 64 | Freq of Lys-His | 1.0 | Important |
| 15 | Freq of Val-Leu | 1.0 | Important | 65 | Freq of Phe-Ile | 1.0 | Important |
| 16 | Freq of Ser-Phe | 1.0 | Important | 66 | Freq of sulfur | 1.0 | Important |
| 17 | Freq of Val-Gln | 1.0 | Important | 67 | Freq of Ser-His | 1.0 | Important |
| 18 | Freq of Phe-Leu | 1.0 | Important | 68 | Freq of Lys-Val | 1.0 | Important |
| 19 | Freq of Asp-Trp | 1.0 | Important | 69 | Freq of Leu-Ser | 1.0 | Important |
| 20 | Freq of Gly-Leu | 1.0 | Important | 70 | Freq of His-Ser | 1.0 | Important |
| 21 | Freq of Leu-Trp | 1.0 | Important | 71 | Freq of Ala-Phe | 1.0 | Important |
| 22 | Freq of His | 1.0 | Important | 72 | Freq of nitrogen | 1.0 | Important |
| 23 | Freq of Phe | 1.0 | Important | 73 | Freq of Glu-Ser | 1.0 | Important |
| 24 | Freq of Lys | 1.0 | Important | 74 | Freq of Arg | 1.0 | Important |
| 25 | Freq of Tyr-Trp | 1.0 | Important | 75 | Freq of Met-Gly | 1.0 | Important |
| 26 | Freq of Gln-Leu | 1.0 | Important | 76 | Freq of Ile-Thr | 1.0 | Important |
| 27 | Freq of Leu-Val | 1.0 | Important | 77 | Freq of Pro-Leu | 1.0 | Important |
| 28 | Freq of Cys-Tyr | 1.0 | Important | 78 | Freq of Lys-Ile | 1.0 | Important |
| 29 | Freq of Leu-Lys | 1.0 | Important | 79 | Freq of Try | 1.0 | Important |
| 30 | Freq of Met-Leu | 1.0 | Important | 80 | Freq of Phe-Thr | 1.0 | Important |
| 31 | Freq of Thr-Phe | 1.0 | Important | 81 | Freq of Leu-Pro | 1.0 | Important |
| 32 | Freq of Val-Ile | 1.0 | Important | 82 | Freq of Ile-Val | 1.0 | Important |
| 33 | Freq of Leu-Gly | 1.0 | Important | 83 | Freq of Ile-Trp | 1.0 | Important |
| 34 | Freq of Gly-Ile | 1.0 | Important | 84 | Count of Trp-Lys | 1.0 | Important |
| 35 | Freq of Hydrophobic | 1.0 | Important | 85 | Freq of His-Leu | 1.0 | Important |
| 36 | Freq of Tyr-Lys | 1.0 | Important | 86 | Freq of Gly-Ala | 1.0 | Important |
| 37 | Freq of Thr-Val | 1.0 | Important | 87 | Freq of Ala-Val | 1.0 | Important |
| 38 | Freq of Ile-Asn | 1.0 | Important | 88 | Count of Trp-Pro | 1.0 | Important |
| 39 | Freq of His-Gln | 1.0 | Important | 89 | Freq of Val-Pro | 1.0 | Important |
| 40 | Freq of Glu-Gly | 1.0 | Important | 90 | Freq of Ser-Ile | 1.0 | Important |
| 41 | Freq of Leu-Tyr | 1.0 | Important | 91 | Freq of Glu-Lys | 1.0 | Important |
| 42 | Freq of Met-Arg | 1.0 | Important | 92 | Freq of oxygen | 1.0 | Important |
| 43 | Freq of Ala-Leu | 1.0 | Important | 93 | Freq of Thr-Leu | 1.0 | Important |
| 44 | Freq of Gln-Met | 1.0 | Important | 94 | Freq of Leu-Cys | 1.0 | Important |
| 45 | Freq of Trp-Leu | 1.0 | Important | 95 | Freq of Ile-Leu | 1.0 | Important |
| 46 | Freq of Thr-His | 1.0 | Important | 96 | Freq of Leu-Ala | 1.0 | Important |
| 47 | Freq of Ile-Arg | 1.0 | Important | 97 | Freq of Phe-Val | 1.0 | Important |
| 48 | Freq of Pro-Val | 1.0 | Important | 98 | Freq of Thr-Lys | 1.0 | Important |
| 49 | Freq of Tyr-Phe | 1.0 | Important | 99 | Freq of Tyr | 1.0 | Important |
| 50 | Count of hydrogen | 1.0 | 100 | Freq of Glu-Ala | 1.0 | Important | |
The algorithm considers one attribute at a time to determine how well each predictor alone predicts the target variable. The important value for each variable is then cal-culated as (1-p), where p is the p value of the appropriate test of association between the candidate predictor and the target variable. Since the target value was categorical, p values based on the F statistic was used.