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. 2011 Jun 17;6(6):e20665. doi: 10.1371/journal.pone.0020665

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Lavra et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Representative immunohistochemical analysis of HIPK2, Gal-3 and Cyclin D1 in PTC. Arrows indicate positive immunostaining for HIPK2 (upper panel) and Cyclin D1 (lower, right panel) into the nuclear compartment of respectively normal and papillary thyroid cells. In the lower left panel is clearly visible cytoplasmic expression of Gal-3 in tumoural tissue. (B) The histogram shows, for each histotype, the percentage of positive cases at the immunohistochemical expression analysis for HIPK2 (white bars) and Gal-3 (black bars).