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. 2011 Jun 17;6(6):e20321. doi: 10.1371/journal.pone.0020321

Figure 3. Results of the meta-analysis of FHS and AGRE for three recombination phenotypes.

Figure 3

Each row consists of a Q-Q plot of observed against expected p-values (left panel) and a Manhattan plot showing the observed p-values across the genome (right panel). A. For the male mean rate. In the Manhattan plot, SNPs at RNF212 are circled in red and new candidate associations discussed in the main text are circled in blue. B. For the female mean rate. In the Manhattan plot, SNPs at or near Inversion 17q21.3 are circled in red and new candidate associations discussed in the main text are circled in blue. C. For the historical hotspot usage in the two sexes. SNPs near PRDM9 are circled in red and a new candidate association discussed in the text is circled in blue.