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. 2011 May 31;10:7. doi: 10.1186/1477-5751-10-7

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Copyright ©2011 Ellison et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Grading of ependymomas in three European trials by five neuropathologists (phase 3 of study). (a) Proportions of tumors classified as grade II (dark gray) or grade III (light gray) among trial cohorts. (b) Proportions of tumors classified as grade II (dark gray) or grade III (light gray) in two trial cohorts (SFOP & CNS9904) before (phase 1; pre-TR) or after (phase 3; post-TR) review of CNS9204 cohort in phase 2 of study (TR). (c) Proportions of tumors in three trial cohorts for which at least 4 of the 5 neuropathologists agreed on grade.