Table 1. BC patients with detectable ESO Ab and/or ESO expression and characteristics of the corresponding tumors.
Patient | ESO Ab | ESO exp* | ER† | PR† | HER2‡ | Age§ | SBR∥ | Histological type | Other tumors | Survival§§ | Relapse | Family history∫∫ |
NB1/78 | + | na | − | − | − | 26 | III | IDC†† | - | D | Liver | + |
NB1/11 | + | + | − | − | + | 61 | III | IDC | Meningioma | A | - | + |
NB5/35 | + | + | − | − | nd | 52 | up** | up | - | A | - | − |
NB1/27 | + | + | − | − | − | 59 | III | IDC | - | A | - | − |
NB15/55 | + | na | − | − | − | 48 | up | up | Cervical | A | - | + |
NB1/41 | + | + | − | − | − | 61 | III | IDC | - | A | Skin, LN | + |
NB1/4 | + | + | − | − | − | 57 | III | IDC | - | A | - | − |
NB14/73 | + | na | − | − | + | 68 | III | IDC | - | A | - | − |
NB1/17 | + | + | − | − | − | 37 | III | IDC | - | D | LN | + |
NB7/6 | + | + | − | − | + | 65 | III | IDC | Spinocellular | A | - | − |
NB14/56 | + | + | − | − | − | 66 | III | MBC‡‡ | - | A | - | − |
NB2/67 | + | − | + | − | − | 71 | I | IDC | Melanoma | A | - | − |
NB1/8 | − | + | − | − | − | 65 | II | IDC | - | A | - | + |
NB1/13 | − | + | − | − | − | 48 | III | IDC | - | A | - | − |
NB1/15 | − | + | − | − | − | 56 | II | IDC | - | D | Pleural, skin, LN | + |
NB1/26 | − | + | − | − | − | 65 | III | IDC | - | A | - | − |
NB1/37 | − | + | − | − | + | 83 | III | ILC∫ | - | A | - | − |
NB1/38 | − | + | − | − | − | 55 | III | Basal-like | - | A | - | − |
NB1/47 | − | + | − | − | − | 58 | III | IDC | - | A | - | − |
NB1/80 | − | + | − | − | − | 74 | III | IDC | - | D | Skin | − |
NB1/85 | − | + | − | − | − | 42 | III | MBC | - | A | - | + |
NB14/78 | − | + | − | − | − | 62 | III | IDC | - | A | - | − |
ESO mRNA expression in frozen tumor specimens was assessed by RT-PCR. na, not available.
ER and PR expression was assessed by IHC staining of paraffin-embedded tumor specimens.
HER2 was assessed by IHC staining in paraffin-embedded tumor specimens and gene amplification was confirmed by FISH analysis. nd, not done.
Age at diagnosis.
SBR, Scarff-Bloom-Richardson tumor grade.
Lymph node metastasis with unknown primary (up).
IDC, invasive ductal carcinoma.
MBC, medullary breast cancer.
ILC, invasive lobular carcinoma.
D, dead; A, alive.
Known family history of breast cancer.