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. 2011 Jun 17;6(6):e21165. doi: 10.1371/journal.pone.0021165

Figure 2. Fbxo7 expression enhances the proliferation of p53 null cells grown at a reduced SCF concentration.

Figure 2

(A) FACS plot of EdU incorporation, showing forward scatter (FSC) on the x-axis and (SSC) side scatter on the y-axis for the left hand panels, with the gated population used for EdU analysis and anti-EdU conjugated to Alexafluor647 on the x-axis and propidium iodide intensity on the y-axis for the right hand panels. (B) Immunoblotting for the expression of various cell cycle regulators, as indicated, in WT and p53 null cells expressing Fbxo7 or the empty MSCV vector. (C) Immunoblotting for Cdk6 in immunoprecipitations of D-type cyclins from equal numbers of sorted WT cells expressing either Fbxo7 or the empty MSCV vector.