Figure 5. Khc is essential for photoreceptor morphogenesis.

khc⁸ mosaic clone in mid-stage (50% pd) pupal Drosophila photoreceptors. (A–E) khc⁸ drosophila photoreceptors stained for Crb (apical marker, red), and E-cad (AJ marker, blue). (A′–E′) khc⁸ mutant photoreceptors were marked by the absence of GFP (green). As the cross sections move more proximally (A–E) both the apical Crb domain (red) and the AJs (blue) show increasingly severe defects. Crb (red) is misshapen at the distal section (A, B) and almost absent at the proximal section (E) from the same pupal eye. (F) Developing pupal photoreceptors elongate from distal to proximal direction. Distal (A, B) and proximal (D, E) sections are marked by dashed-lines.