Table 2.
Increased Dio3, and decreased TRα1 and GR protein and mRNA levels in alcohol-exposed (E) placentae.
Group | Protein | mRNA | |
---|---|---|---|
Dio3 | C | 1.30± 0.01 | 0.34± 0.07 |
PF | 1.44± 0.14 | 0.27± 0.04 | |
E | 1.86± 0.07*/# | 0.86± 0.23*/# | |
TRα1 | C | 0.97± 0.04 | 1.11± 0.09 |
PF | 0.88± 0.05 | 1.12± 0.16 | |
E | 0.74± 0.04* | 0.60± 0.07*/# | |
GR | C | 0.92± 0.03 | 1.25± 0.08 |
PF | 0.85± 0.09 | 1.33± 0.11 | |
E | 0.72± 0.06*/# | 0.75± 0.07*/# |
Placental protein and mRNA levels of male fetuses on G21 were normalized to β-actin and GAPDH, respectively. Values are shown as means +/− SEM,
p<0.05 from control (C) placenta and
p<0.05 from pair fed (PF) placenta.