Table 1.
Baseline Characteristics of Patients With and Without Stroke in the Territory of the Symptomatic Stenotic Artery Subsequent to Randomization*
| Characteristic | # of Patients with Data |
Stroke in the Territory (n=42) |
No Stroke in the Territory (n=245) |
P-value |
|---|---|---|---|---|
| Age (Yrs) | 287 | 61.5 ± 12.8 | 63.9 ± 11.7 | 0.22 |
| Sex | 0.33 | |||
| Male | 183 | 24 (13) | 159 (87) | |
| Female | 104 | 18 (17) | 86 (83) | |
| Race | 0.44 | |||
| Black | 79 | 15 (19) | 64 (81) | |
| White | 169 | 22 (13) | 147 (87) | |
| Other | 39 | 5 (13) | 34 (87) | |
| Height (in) | 281 | 67.2 ± 3.9 | 67.1 ± 3.9 | 0.84 |
| Weight (lb) | 284 | 182.8 ± 39.1 | 183.1 ± 37.4 | 0.96 |
| Body mass index (kg/m2) | 280 | 28.2 ± 4.5 | 28.6 ± 5.1 | 0.65 |
| Blood pressure (mmHg) | ||||
| Systolic | 286 | 139.9 ± 14.6 | 139.6 ± 16.8 | 0.89 |
| Diastolic | 286 | 75.9 ± 9.9 | 77.0 ± 10.4 | 0.52 |
| Laboratory lipids (mg/dl) | ||||
| HDL | 245 | 41.9 ± 9.5 | 42.8 ± 11.7 | 0.66 |
| LDL | 239 | 126.0 ± 46.7 | 122.1 ± 36.4 | 0.58 |
| Drinks alcohol | 0.95 | |||
| No | 172 | 24 (15) | 147 (85) | |
| Yes | 115 | 17 (15) | 98 (85) | |
| Ever smoked | 0.86 | |||
| No | 106 | 15 (14) | 91 (86) | |
| Yes | 181 | 27 (15) | 154 (85) | |
| Activity level | 0.84 | |||
| Sedentary | 72 | 10 (14) | 62 (86) | |
| Not Sedentary | 215 | 32 (15) | 183 (85) | |
| History of ischemic stroke | 0.46 | |||
| No | 218 | 30 (14) | 188 (86) | |
| Yes | 63 | 11 (17) | 52 (83) | |
| History of TIA | 0.30 | |||
| No | 208 | 34 (16) | 174 (84) | |
| Yes | 71 | 8 (11) | 63 (89) | |
| History of coronary artery disease | 0.094 | |||
| No | 208 | 26 (12) | 182 (88) | |
| Yes | 73 | 15 (21) | 58 (79) | |
| History of hypertension | 0.63 | |||
| No | 41 | 5 (12) | 36 (88) | |
| Yes | 245 | 37 (15) | 208 (85) | |
| History of diabetes | 0.16 | |||
| No | 178 | 22 (12) | 156 (88) | |
| Yes | 109 | 20 (18) | 89 (82) | |
| History of lipid disorder | 0.82 | |||
| No | 81 | 11 (14) | 70 (86) | |
| Yes | 198 | 29 (15) | 169 (85) | |
| NIH Stroke Scale score | 0.007 | |||
| 0–1 | 195 | 21 (11) | 174 (89) | |
| >1 | 92 | 21 (23) | 71 (77) | |
| Qualifying event | 0.016 | |||
| Stroke | 124 | 11 (9) | 113 (91) | |
| TIA | 163 | 31 (19) | 132 (81) | |
| Symptomatic vessel | 0.99 | |||
| Anterior | 130 | 19 (15) | 111 (85) | |
| Posterior | 157 | 23 (15) | 134 (85) | |
| Percent stenosis of symptomatic artery | 0.097 | |||
| 50–69% | 170 | 20 (12) | 150 (88) | |
| 70–99% | 117 | 22 (19) | 95 (81) | |
| On antithrombotic therapy at qualifying event | 0.83 | |||
| No | 127 | 18 (14) | 109 (86) | |
| Yes | 159 | 24 (15) | 135 (85) | |
| Time from qualifying event to enrollment | 0.17 | |||
| ≤ 17 days | 143 | 25 (17) | 118 (83) | |
| > 17 days | 144 | 17 (12) | 127 (88) | |
| Treatment assignment | 0.82 | |||
| Aspirin | 132 | 20 (15) | 112 (85) | |
| Warfarin | 155 | 22 (14) | 113 (86) | |
*
Values in the table are mean ± standard deviation or number (%)