Table 2.
Univariate Associations of Baseline Characteristics With Stroke in the Territory of the Symptomatic Stenotic Artery (n=287)
| Characteristic | HR (95% CI) | P-value |
|---|---|---|
| Age (≥64 vs <64 yr) | 0.58(0.31–1.08) | 0.087 |
| Sex (female vs male) | 1.46(0.79–2.69) | 0.225 |
| Race (other vs white) | 1.37(0.79–2.51) | 0.310 |
| Height (>67 vs ≤ 67 in) | 1.03(0.55–1.92) | 0.926 |
| Weight (>180 vs ≤ 180 lbs) | 0.83(0.45–1.54) | 0.557 |
| Body mass index (≥25 vs < 25 kg/m2) | 1.67(0.74–3.77) | 0.220 |
| SBP (≥140 vs <140) | 0.64(0.34–1.21) | 0.170 |
| DBP (≥80 vs < 80) | 0.62(0.33–1.16) | 0.133 |
| LDL (≥100 vs < 100) | 0.84(0.41–1.73) | 0.645 |
| HDL (<40 vs ≥ 40) | 0.99(0.51–1.92) | 0.966 |
| Drinks alcohol (yes vs no) | 1.01(0.55–1.88) | 0.964 |
| Ever smoked (yes vs no) | 1.04(0.56–1.96) | 0.893 |
| Activity level (sedentary vs other) | 0.91(0.45–1.85) | 0.795 |
| History of ischemic stroke (yes vs no) | 1.32(0.66–2.63) | 0.433 |
| History of TIA (yes vs no) | 0.68(0.31–1.46) | 0.323 |
| History of coronary arterial disease (yes vs no) | 1.75(0.93–3.32) | 0.084 |
| History of hypertension (yes vs no) | 1.25(0.49–3.18) | 0.639 |
| History of diabetes (yes vs no) | 1.52(0.83–2.79) | 0.172 |
| History of lipid disease (yes vs no) | 1.05(0.53–2.10) | 0.888 |
| NIH Stroke Scale score (>1 vs ≤ 1) | 2.27(1.24–4.15) | 0.008 |
| Qualifying event (stroke vs TIA) | 2.41(1.21–4.80) | 0.013 |
| Symptomatic vessel (posterior vs anterior) | 1.00(0.55–1.84) | 0.997 |
| Percent stenosis (≥ 70% vs < 70%) | 1.72(0.94–3.16) | 0.079 |
| On antithrombotic therapy at qualifying event (yes vs no) | 1.03(0.56–1.90) | 0.919 |
| Time from qualifying event to enrollment (≤ 17 vs > 17 days) | 1.70(0.91–3.15) | 0.094 |
| Treatment assignment (aspirin vs warfarin) | 1.08(0.59–1.98) | 0.797 |
| Collaterals None vs. Good Poor vs. Good |
1.14 (0.39–3.30) 4.36 (1.46–13.07) |
0.0001 |