Fig. 4.

Cardiac 123-iodine metaiodobenzylguanidine (123-I MIBG) imaging allows prediction of ventricular arrhythmias causing appropriate implantable cardioverter-defibrillator (ICD) therapy in heart failure patients. Patients with a large defect on late 123-I MIBG SPECT imaging (summed defect score > 26) showed significantly more ventricular arrhythmias when compared to patients with a small defect on late 123-I MIBG SPECT imaging (summed defect score ≤ 26) at 3-year of follow-up (52 vs. 5%, P < 0.01). Reprinted with permission from reference 47