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. Author manuscript; available in PMC: 2012 Jan 1.
Published in final edited form as: Per Med. 2011 Mar;8(2):161–173. doi: 10.2217/pme.11.7

Figure 1. Hypothetical outcomes associated with two individual n-of-1 trials investigating the efficacy of two different antihypertensive medications.

Figure 1

The wavy dark and light lines reflect the SBP levels for individuals 1 and 2, respectively, during the trial. The design included a baseline period followed by four alternating periods in which two drugs, A and B, were administered with a washout period between drug administrations. Note that individual 1 had better blood pressure control while on drug A, as indicated by the horizontal lines denoting ‘drug A’ and ‘drug B’, which reflect the average blood pressure achieved while on the drugs. Individual 2 had better blood pressure control on drug B.

SBP: Systolic blood pressure.