Table 3.
Antinociceptive Effect of a Single Treatment of V. ashei Extract on the Tail-Flick Test
| |
Latency (minutes) |
|||||
|---|---|---|---|---|---|---|
| Treatment (mg/kg) | 0 | 30 | 60 | 90 | 120 | 150 |
| Control | 8.4 ± 1.4 | 11.9 ± 2.3 | 12.8 ± 1.2 | 12.4 ± 0.8 | 13.1 ± 1.0 | 13.2 ± 1.4 |
| Morphine (10) | 8.8 ± 1.9 | 30.0 ± 0.0* | 29.4 ± 0.6* | 28.1 ± 1.4* | 24.5 ± 2.7* | 26.2 ± 2.6* |
| Extract (6.4) | 7.0 ± 0.7 | 23.4 ± 2.8* | 23.8 ± 2.7* | 24.7 ± 2.2* | 26.90 ± 1.3* | 26.4 ± 1.8* |
Data are mean ± SEM values for 10 animals per group. Student-Newman-Keuls analysis shows that the morphine, extract (3.2 mg/kg), and extract (6.4 mg/kg) groups at 30, 60, 90, 120, and 150 minutes after administration are significantly different from the control group (*P < .05).