Table 5.
Parameter estimates of the population MCV model
| Parameters | Typical values (95% CI) | SD of IIV (95% CI) | Interindividual CV |
|---|---|---|---|
| Kin (%/day) | 3.71 (3.13 - 4.30) | 0.191 (0.083 - 0.401) | 19% |
| Kout (day-1) | 0.042 (0.035 - 0.048) | 0.186 (0.044 - 0.415) | 19% |
| β (L. mg-1)1/γ | 0.099 (0.064 - 0.135) | 0.457 (0.336 - 0.599) | 48% |
| γ (unitless) | 0.19 (0.02 - 0.46) | ||
| θΔHbF% (day-1) | 1.22 (-0.07 - 2.21) | ||
| SD of proportional residual error | 0.036 (0.030 - 0.040) | ||
| Correlation (ηKin, ηKout) | 0.87 | ||
| Correlation (ηKin, ηβ) | -0.98 | ||
| Correlation (ηKout, ηβ) | -0.95 |
CI: confidence intervals, obtained by bootstrap (n = 1000), SD: standard deviation, IIV: interindividual variability, CV: the apparent coefficient of variation of interindividual variability.