Table 1.

Penetrance values for simulation settings

	additive model			dominant model			recessive model
	104 × f0	104 × f1	104 × f2	104 × f0	104 × f1	104 × f2	104 × f0	104 × f1	104 × f2
r = 3
p = 0.1	71	214	357	72	217	217	98	98	294
p = 0.25	50	150	250	53	160	160	89	89	267
p = 0.5	33	100	167	40	120	120	67	67	200
r = 2.5
p = 0.1	77	192	308	78	195	195	99	99	246
p = 0.25	57	143	229	60	151	151	91	91	229
p = 0.5	40	100	160	47	118	118	73	73	182
r = 2
p = 0.1	83	167	250	84	168	168	99	99	198
p = 0.25	67	133	200	70	139	139	94	94	188
p = 0.5	50	100	150	57	114	114	80	80	160

Numbers listed are scaled penetrance values (10⁴ × f₀, 10⁴ × f₁, 10⁴ × f₂) corresponding to different allele frequencies (p) and relative ratios (r) under three genetic models

The prevalence K is set at 0.01